EBF
EBF Open Symposium
EBF Barcelona
EBF 8th Open Meeting
Into New Territories - Explore, Learn and Apply
EBF 2nd YSS
Hesperia Tower Conference Centre
Barcelona, Spain
November 17, 2015
YSS
November 18-20, 2015
Open Symposium

Future of Bioanalysis… A Bridge between Industry and Academia

YSS Program

 

08:30  08:35  Welcome and Introduction
08:35 09:35 Expect the Unexpected
08:35 08:45 Ils Pijpers (Janssen R&D)
Identification and mitigation of an unexpected interference  in plasma samples originating from a special population PK study
08:45 08:55 Alison Cooper (MedImmune)
Challenges and Considerations for the Development of Ligand Binding Assays for
Novel Antibody Fusions
08:55 09:05 Rajasekhar Thotakura (Envigo)
A Strategic Approach for Dealing with Variable Adduct Formation and Irreversible
Protein Binding for LC-MS/MS Applications
09:05 09:15 Pierre-Yves Caron (InVentivHealth)
Robust  Sample Analysis: The Importance of Method Development.
09:15 09:25 Elli Oksanen (Syrinx Bioanalytics)
Universal detection reagent for immunogenicity assays in cynomolgus monkey samples
09:25 09:35 Panel Discussion
09:35 11:05 Rise of the Large Molecules
09:35 09:50 James Howard (LGC)
Little to LARGE: LC-MS/MS Peptide Method Development for Small Molecule Specialists
09:50 10:05 Stéphanie Teixeira (NovImmune)
Challenges of inflammatory biomarker assay development and validation
10:05 10:20 Gaetan Chasseigne (Novartis)
Parallelism assessment during method validation for the quantitation of Biologics – Case study of a drug peptide and recommendations
10:20 10:35 Kabir Hussain (MedImmune)
Immunogenicity Testing of Large Molecules & the Challenges of Developing ADA Assays
10:35 10:50 Christelle Pythoud (Celerion)
The Road to Functional Bioanalysis: Development and Validation of a Cell-Based Assay for Neutralizing Anti-Drug Antibody Analysis
10:50 11:05 Q & A
11:05 11:20 Coffee break
11:20 12:10 The LLOQ is not enough
11:20 11:30 Liz Hickford (UCB BioPharma)
Development of an accurate and sensitive ELISA for the measurement of TNF in clinical samples
11:30 11:40 Suzy Geerinckx (Janssen R&D)
LC–MS/MS method for simultaneous quantification of Prostaglandins in colon polyps and punches.
11:40 11:50 Francotte Antoine (UCB BioPharma / HELHa)
Application of Immunocapture sample pretreatment for improved specificity and sensitivity
11:50 12:00 Victoria Jennings (Covance)
The analysis of Clobetasol and Clobetasol-17-propionate in human plasma by LC-MS/MS
12:00 12:10 Panel Discussion
12:10 12:20 Poster Pitch
12:20 13:10 Lunch break
13:10 14:40 To Infinity and Beyond
13:10 13:25 Sara Capiau (University of Ghent)
A novel non-contact method to estimate the hematocrit of dried blood spots.
13:25 13:40 Michele Protti (University of Bologna)
Dried urine microsamples: a novel strategy  for LC-MS/MS analysis of oxycodone and metabolites
13:40 13:55 Karl Pettersson (Ferring Pharmaceuticals A/S)
Evaluation of a promising new homogenous assay technology (SPARCL) and comparisons with MSD, using FSH in human serum, as test substance
13:55 14:10 James Beecroft (Envigo)
Use of Design of Experiments (DoE) Software to quickly and successfully develop immunoassay methods
14:10 14:25 Tinne Huybrechts (Janssen R&D)
The development of a sensitive LC-MS/MS assay for analysis of stable isotope labeled microdose exposure in the presence of therapeutic drug levels in human volunteers
14:25 14:40 Q & A
14:40 15:10 Tricks of the Trade – This session will be led by you the audience
Carryover issues
Unusual Matrices
Instability & ISR failures
Defining a blank matrix with endogenous analytes
Cutpoints and positive controls in immunogenicity
15:10 15:25 Tea break
15:25 16:40 Bridging the Bioanalytical Community
15:25 15:40 Bert Rutten (LGC)
A personal perspective on moving between academia and industry:“A Journey from Industry to Academia and Back”
15:40 15:55 Sílvia M. Illamola (Unité de recherche Clinique – Hôpital Cochin, Paris)
Plasma Protein Binding, new approaches and challenges for this kind of bioanalysis
15:55 16:10 Jason Bilodeau (InVentivHealth)
Reaching lower limits of quantification by LC-MS/MS : The quest for  sensitivity
16:10 16:25 Apoorva Kotian (UCB BioPharma)
Higher throughput approaches towards the absolute quantitation of drug metabolising enzymes and membrane transporters in complex matrices
16:25 16:40 Q & A
16:40 16:55 Poster Prize and Wrap-up
16:55 17:00 Adjourn